LONDON -- The shares of�AstraZeneca� (LSE: AZN ) (NYSE: AZN ) added 6 pence to 3,359 pence during early London trade this morning after the company said it will write off $140 million following the outcome of a product trial.
The FTSE 100 member confirmed the charge related to the development of fostamatinib, an oral treatment for rheumatoid arthritis, and would be taken in the second quarter.
AstraZeneca said the results from a phase 3 test program, alongside data reported previously from earlier trials, had prompted the company not to proceed with regulatory filings for the product.
The blue chip also claimed that hypertension, diarrhea, nausea, headache, and nasopharyngitis were among the treatment's most commonly reported side effects.
AstraZeneca said it would now return the rights for fostamatinib to�Rigel Pharmaceuticals.
Briggs Morrison, managing director, executive vice president of global medicines development and chief medical officer at AstraZeneca, said:
Top 5 Blue Chip Stocks To Buy Right Now: International Business Machines Corporation(IBM)
International Business Machines Corporation (IBM) provides information technology (IT) products and services worldwide. Its Global Technology Services segment provides IT infrastructure and business process services, including strategic outsourcing, process, integrated technology, and maintenance services, as well as technology-based support services. The company?s Global Business Services segment offers consulting and systems integration, and application management services. Its Software segment offers middleware and operating systems software, such as WebSphere software to integrate and manage business processes; information management software for database and enterprise content management, information integration, data warehousing, business analytics and intelligence, performance management, and predictive analytics; Tivoli software for identity management, data security, storage management, and datacenter automation; Lotus software for collaboration, messaging, and so cial networking; rational software to support software development for IT and embedded systems; business intelligence software, which provides querying and forecasting tools; SPSS predictive analytics software to predict outcomes and act on that insight; and operating systems software. Its Systems and Technology segment provides computing and storage solutions, including servers, disk and tape storage systems and software, point-of-sale retail systems, and microelectronics. The company?s Global Financing segment provides lease and loan financing to end users and internal clients; commercial financing to dealers and remarketers of IT products; and remanufacturing and remarketing services. It serves financial services, public, industrial, distribution, communications, and general business sectors. The company was formerly known as Computing-Tabulating-Recording Co. and changed its name to International Business Machines Corporation in 1924. IBM was founded in 1910 and is based in Armonk, New York.
Advisors' Opinion:- [By Kate Gibson]
After a near 117-point fall, the Dow Jones Industrial Average (DJIA) �was lately off 71.73 points, or 0.5%, to 15,256.57, with Cisco Systems Inc. (CSCO) , Intel Corp. (INTC) � and International Business Machines Corp. (IBM) �among the top decliners.
- [By Dan Caplinger]
Still, those results haven't changed GE's general strategic plan as it strengthens its reach into various industrial sectors. Its vision of what it calls the "industrial Internet" put it on a collision course with IBM (NYSE: IBM ) , whose Big Data initiative has similar goals of providing interconnections across networks of equipment to provide information that companies can use to cut costs and monitor operations. IBM has used its technology expertise to attract interest from clients and bolster its high-margin earnings growth, but GE has a closer connection to the actual equipment that will provide data to users. General Electric has also continued to become a bigger player in energy, combining its renewable-energy expertise with its recent purchase of Lufkin Industries to add traditional oil and gas services to its portfolio of offerings to customers.
Top 5 Blue Chip Stocks To Buy Right Now: Philip Morris International Inc(PM)
Philip Morris International Inc., through its subsidiaries, engages in the manufacture and sale of cigarettes and other tobacco products in markets outside of the United States. Its international product brand line comprises Marlboro, Merit, Parliament, Virginia Slims, L&M, Chesterfield, Bond Street, Lark, Muratti, Next, Philip Morris, and Red & White. The company also offers its products under the A Mild, Dji Sam Soe, and A Hijau in Indonesia; Diana in Italy; Optima and Apollo-Soyuz in the Russian Federation; Morven Gold in Pakistan; Boston in Colombia; Belmont, Canadian Classics, and Number 7 in Canada; Best and Classic in Serbia; f6 in Germany; Delicados in Mexico; Assos in Greece; and Petra in the Czech Republic and Slovakia. It operates primarily in the European Union, Eastern Europe, the Middle East, Africa, Asia, Canada, and Latin America. The company is based in New York, New York.
Advisors' Opinion:- [By Rupert Hargreaves]
After a�record�first half, tobacco stocks are now starting to pull back as the high-yield sector of the market is sold-off. During the first six and a half months of the year, Altria (NYSE: MO ) matched the S&P 500 with gains of 17.5%, while�Reynolds American (NYSE: RAI ) �climbed 24% and Philip Morris International (NYSE: PM ) �advanced�7.3%, all excluding dividends (the S&P 500 gained 18% over the same period). However, since the recent sell-off began, all three companies have wiped out most of their gains so far this year.��
Top 5 Penny Stocks To Invest In 2014: Visa Inc.(V)
Visa Inc., a payments technology company, engages in the operation of retail electronic payments network worldwide. It facilitates commerce through the transfer of value and information among financial institutions, merchants, consumers, businesses, and government entities. The company owns and operates VisaNet, a global processing platform that provides transaction processing services. It also offers a range of payments platforms, which enable credit, charge, deferred debit, debit, and prepaid payments, as well as cash access for consumers, businesses, and government entities. The company provides its payment platforms under the Visa, Visa Electron, PLUS, and Interlink brand names. In addition, it offers value-added services, including risk management, issuer processing, loyalty, dispute management, value-added information, and CyberSource-branded services. The company is headquartered in San Francisco, California.
Advisors' Opinion:- [By Sean Williams]
You must be at least "this employed" to participate in our budget
It all started earlier this week for McDonald's, which insulted the very core of its customer base by teaming up with Visa (NYSE: V ) to create a budget planning website that it dubbed "Practical Money Skills for Life." The idea is actually a great one as citizens young and old of upper and lower incomes can always use the reminder and education about how to balance their income and spending. The execution, though, left a lot to be desired. - [By Selena Maranjian]
Visa (NYSE: V ) saw its global brand value surge 46%, to $56 billion. The company is extremely global, operating in more than 200 nations, and it's poised to profit as more and more people and businesses shift from cash transactions to electronic ones. Its presence in emerging markets is also a good thing to see among stock picks, as such economies are growing rapidly -- and for Visa, that means more people beginning to use plastic for purchases. Meanwhile, our recovering economy is leading to an uptick in credit payments. The fast-growing company's forward P/E is 21, well below its five-year average of 41. Visa is far bigger than its rivals, although�MasterCard�is doing particularly well globally.
- [By Ben Levisohn]
Financial stocks are taking the brunt of the damage this morning. The Financial Select Sector SPDR ETF (XLF) has dropped 1.1% to $129.83 at 9:38 a.m., making it the biggest loser among sector ETFs. Visa (V) and American Express (AXP) have dropped 1.8% and 1.7%, to lead the Dow lower.
Top 5 Blue Chip Stocks To Buy Right Now: Apple Inc.(AAPL)
Apple Inc., together with subsidiaries, designs, manufactures, and markets personal computers, mobile communication and media devices, and portable digital music players, as well as sells related software, services, peripherals, networking solutions, and third-party digital content and applications worldwide. The company sells its products worldwide through its online stores, retail stores, direct sales force, third-party wholesalers, resellers, and value-added resellers. In addition, it sells third-party Mac, iPhone, iPad, and iPod compatible products, including application software, printers, storage devices, speakers, headphones, and other accessories and peripherals through its online and retail stores; and digital content and applications through the iTunes Store. The company sells its products to consumer, small and mid-sized business, education, enterprise, government, and creative markets. As of September 25, 2010, it had 317 retail stores, including 233 stores in the United States and 84 stores internationally. The company, formerly known as Apple Computer, Inc., was founded in 1976 and is headquartered in Cupertino, California.
Advisors' Opinion:- [By Canadian Value]
Position % of Fund Assets 1) First American Financial Corp. (FAF) 7.0% 2) Apple, Inc. (AAPL) 6.5% 3) Coinstar, Inc. (CSTR) 4.8% 4) EMC Corp. (EMC) 4.4% 5) Coach, Inc. (COH) 4.4% 6) Kohl's Corp. (KSS) 4.1% 7) Blucora, Inc. (BCOR) 4.0% 8) Tetra Tech, Inc. (TTEK) 3.1% 9) OM Group, Inc. (OMG) 3.0% 10) American International Group, Inc. (AIG) 2.8% TOTAL 44.1% One area that we believe still offers some value in the market is in high quality, large��ap technology stocks that may be momentarily out��f��avor as they transition from rapid growth to slower growth. In particular, we become interested when that transition is also accompanied by a change in capital allocation policies designed to return more cash to shareholders in the form of dividends and share repurchases. We believe that Apple and EMC are two of the absolute highest quality technology businesses in the world and both have recently announced very material, shareholder��friendly changes to how they will allocate capital.
- [By Zenway Investing]
Online-only competitors like Amazon (AMZN) have thrived off of Best Buy�� spacious and colorful showroom, making it a destination for testing products but not for buying. The Apple (AAPL) brand has established itself as the wave of the future with its signature products and revolutionary retail stores. Both companies have many other things that Best Buy doesn�� have at the moment. Apple and Amazon operate a successful internet-based business. They provide high-quality customer service that actually leads to high customer satisfaction. They are programmed for basic inventory management.
- [By Rick Munarriz]
1. Apple will close higher on the week
It's time for Apple (NASDAQ: AAPL ) to shine. The consumer-tech giant has been a disappointing investment since the iPhone 5 came out, and it probably doesn't help matters that many of Apple's tech peers posted uninspiring quarterly results this past week.
Top 5 Blue Chip Stocks To Buy Right Now: McDonald's Corporation(MCD)
McDonald?s Corporation, together with its subsidiaries, operates as a worldwide foodservice retailer. It franchises and operates McDonald?s restaurants that offer various food items, soft drinks, coffee, and other beverages. As of December 31, 2009, the company operated 32,478 restaurants in 117 countries, of which 26,216 were operated by franchisees; and 6,262 were operated by the company. McDonald?s Corporation was founded in 1948 and is based in Oak Brook, Illinois.
Advisors' Opinion:- [By Douglas A. McIntyre]
The�Fast Food Forward movement to increase pay for people who work at fast-food companies like McDonald�� Corp. (NYSE: MCD)�and Yum! Brands Inc. (NYSE: YUM)�seems to have a fair point. These workers cannot live much above the poverty level if they make only $7.25 an hour, or even $8 or $9. The movement continues to push for a pay level of $15 an hour. Whether or not�that hourly figure would lift these workers to a level where they make enough to support them at a lower middle class level, one aspect of the movement has undercut the Fast Food Forward efforts and will continue to do so. The leader of one of the movement’s largest supporters, the�Service Employees International Union (SEIU), makes well in excess of $250,000 a year. As a matter for fact, the union’s president,�Mary Kay Henry, made nearly $300,000 in 2011.
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